Masters Medspa — Irvine, Orange County CA
Hormone Therapy & Wellness
BioTe | Peptides | NAD | Women & Men | Longevity
Feeling like yourself again starts from the inside. At Masters Medspa, our hormone therapy and wellness programs are designed for both women and men — addressing the root causes of fatigue, weight changes, mood shifts, low libido, and hormonal imbalance at every stage of life.
Your Hormone Specialist
Katherine MacBarron, PA-C
Physician Associate | Hormone & Wellness Specialist
Kat MacBarron, PA-C brings a uniquely comprehensive clinical background to hormone and wellness medicine — with experience spanning OB/GYN, plastic surgery, and medical aesthetics. Her deep understanding of women's and men's health, cellular biology, and the interplay between hormones, metabolism, and aging makes her one of the most trusted wellness providers in Orange County.
Kat's approach is rooted in precision — she begins every program with thorough labs, listens carefully to your symptoms and goals, and builds a protocol that is genuinely tailored to your biology. Her passion is helping patients feel their absolute best from the inside out.
Women's Hormonal Health
Perimenopause & Menopause Support
Perimenopause and menopause represent one of the most significant hormonal transitions in a woman's life — and for many women, the symptoms are far more disruptive than they expected. Hot flashes, night sweats, weight gain, mood swings, brain fog, sleep disruption, and loss of libido are not inevitable parts of aging. They are symptoms of hormonal decline that can be addressed effectively with the right support.
At Masters Medspa, we provide comprehensive perimenopause and menopause care using bioidentical hormone therapy, peptides, and nutraceutical support — designed to restore hormonal balance, relieve symptoms, protect long-term bone and cardiovascular health, and help you feel like yourself again. Treatment is personalized based on your labs, symptoms, and stage of transition.
Men's Hormonal Health
Testosterone & Men's Wellness
Testosterone levels in men begin to decline gradually after age 30 — and for many men, the effects are subtle at first and then increasingly hard to ignore. Low testosterone is one of the most underdiagnosed conditions in men's health, and its symptoms are often dismissed as simply "getting older."
They don't have to be. Testosterone optimization with BioTe bioidentical pellet therapy can meaningfully restore energy, drive, strength, libido, mental clarity, and body composition — helping men feel and perform at their best well into their forties, fifties, and beyond. Our BioTe male pellets last 4 to 6 months and are inserted in a simple, quick in-office procedure.
Bioidentical Hormone Replacement
BioTe Hormone Therapy
BioTe bioidentical hormone pellet therapy is one of the most effective and convenient approaches to hormone replacement available today. Small, rice-sized pellets — made from plant-derived hormones that are chemically identical to those your body produces naturally — are inserted just beneath the skin in a simple in-office procedure.
Unlike oral pills, creams, or injections that create hormonal peaks and valleys throughout the day, BioTe pellets dissolve slowly over several months — releasing hormones in a steady, consistent dose that mirrors your body's natural rhythm. Patients frequently report feeling improvements in energy, sleep, mood, libido, mental clarity, and body composition within weeks of their first treatment.
For Women
BioTe Female Pellet
- Estrogen & testosterone optimization
- Addresses perimenopause & menopause symptoms
- Supports libido, mood, energy & bone density
- Lasts approximately 4 months
- $600 per treatment
For Men
BioTe Male Pellet
- Testosterone optimization
- Addresses low T symptoms & andropause
- Supports strength, libido, drive & body composition
- Mini pellet lasts 4 months — $750
- Standard pellet lasts 6 months — $1,350
Anti-Aging & Longevity
Hormone Optimization for Healthy Aging
Hormonal decline is one of the primary drivers of aging — impacting not just how we look, but how we feel, perform, and recover. Declining levels of estrogen, testosterone, and growth hormone contribute to muscle loss, increased body fat, reduced bone density, cognitive decline, and a general loss of vitality that many people accept as inevitable.
It doesn't have to be. Hormone optimization — when guided by comprehensive lab work and a skilled clinician — can meaningfully slow the aging process, preserve muscle mass and bone density, improve cognitive function, restore energy and motivation, and support a higher quality of life well into your later decades.
At Masters Medspa, Kat takes a proactive, preventive approach to hormonal aging — working with patients not just to relieve current symptoms, but to optimize their hormonal environment for long-term health and resilience. Whether you are in your thirties noticing early changes, navigating perimenopause, or well into post-menopause, there is a protocol designed for where you are right now.
Intimacy & Vitality
Sexual Wellness & Libido Support
Changes in libido, arousal, and sexual satisfaction are among the most common — and least discussed — symptoms of hormonal imbalance. For women, declining estrogen and testosterone levels can lead to reduced desire, vaginal dryness, and discomfort. For men, low testosterone is among the leading causes of reduced libido, erectile dysfunction, and loss of confidence and vitality.
Hormone optimization with BioTe bioidentical pellets is one of the most effective tools available for restoring sexual wellness naturally. By bringing hormone levels back into an optimal range, many patients experience meaningful improvements in desire, arousal, energy, and overall vitality — without synthetic drugs or their side effects.
Cellular Health & Performance
Peptide Therapy
Peptides are short chains of amino acids that act as biological messengers — signaling specific physiological responses throughout the body. When used therapeutically, peptides can support a remarkable range of health and wellness goals including fat metabolism, lean muscle preservation, growth hormone stimulation, immune function, cognitive performance, skin health, and cellular repair.
At Masters Medspa, peptide therapy is prescribed and monitored by Kat as part of a personalized wellness protocol — tailored to your labs, health history, goals, and current hormone status. Peptides are frequently combined with hormone therapy and NAD for patients seeking a comprehensive, integrated approach to aging, performance, and metabolic health.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Cellular Energy & Longevity
NAD Therapy
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every cell of the body that plays a central role in energy production, DNA repair, and cellular metabolism. NAD+ levels naturally decline with age — contributing to fatigue, cognitive decline, slower metabolism, and reduced cellular repair capacity.
NAD therapy replenishes these declining levels, supporting mitochondrial function, boosting energy and mental clarity, improving metabolic efficiency, and enhancing the body's ability to repair and regenerate at the cellular level. Many patients report significant improvements in energy, focus, mood, and overall vitality following a course of NAD treatments.
At Masters Medspa, NAD is available as an IV infusion for rapid, comprehensive cellular delivery — or as a monthly injection series for ongoing metabolic and longevity support. NAD pairs exceptionally well with both peptide therapy and hormone optimization for a fully integrated wellness protocol.
Related Service
Medical Weight Loss
Hormonal imbalance is one of the most common and overlooked contributors to weight gain and difficulty losing weight — making hormone therapy and medical weight loss a natural complement. Our Medical Weight Loss program works alongside hormone optimization to address the metabolic and biological factors that make sustainable weight loss possible.
Learn more about our clinically supervised Medical Weight Loss program — including peptide-based protocols, consultation requirements, and pricing.
View Medical Weight Loss →Consultation & Lab Work
| Labs, Consultation & Tailored Treatment Plan | $400 |
BioTe Hormone Therapy
| BioTe Female Pellet (lasts 4 months) | $600 |
| BioTe Male Pellet Mini (lasts 4 months) | $750 |
| BioTe Male Pellet (lasts 6 months) | $1,350 |
Peptide Therapy
| Peptide Therapy | From $200 / month |
NAD Therapy
| NAD IV Infusion | $650 |
| NAD Injections | $550 / month |
* Consultation and lab work required prior to beginning any hormone or peptide therapy program. Pricing is determined at consultation and may vary based on individual protocol.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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